Extended Data Fig. 5. Close-up view of the interaction of 5’ and 3’ vRNA termini with FluPolR.
a, c, Close-up view of the 3’ vRNA pointing towards the active site in the FluPolC-huANP32A (a) and FluPolC-chANP32A (c) structures. b, d, Close-up view of the 3’ vRNA binding in a groove located between P3CTD and the PB1thumb and PB2N1 subdomains in the FluPolC-huANP32A (b) and FluPolC-chANP32A (d) structures.