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. 2021 May;152:105287. doi: 10.1016/j.nbd.2021.105287

Fig. 5.

Fig. 5

Different DBS frequencies do not change FTG frequency A. Left: Time-frequency spectrogram of representative DBS block. Grey bars above the spectrogram and the vertical dashed lines denote DBS onset and offset. Different DBS frequencies are shown in the grey bars. The black contour surrounds the FTG feature within the ROI (see Methods). PSD shown for the first and second half during DBS and the 5-s reference period after DBS cessation. Grey horizontal line denote the FTG threshold at two standard deviations above average of the respective reference periods. Black arrowheads denote significant PSD peaks. B. Left: Time-frequency spectrogram of DBS at 180 and 190 Hz. Both DBS blocks are separated by DBS bursts (label: DBS bursts) consisting of repetitive periods on and off DBS of variable length. Right: PSD shown for periods during DBS at 180 and 190 Hz and a 5-s reference after DBS ceased. Horizontal line, contours and arrowheads as in A. C + D. FTG frequencies during (C) and after (D) long DBS blocks plotted over DBS frequencies at 130 Hz, 180 Hz and 190 Hz (all blocks from patients 3 and 4). Despite varying DBS frequencies, the FTG stays at a similar frequency. E + F. FTG amplitudes during (E) and after (F) long DBS blocks plotted over DBS frequencies at 130 Hz, 180 Hz and 190 Hz (all blocks from patients 3 and 4). During DBS, FTG amplitudes tend to be increased at higher driving frequencies.