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. Author manuscript; available in PMC: 2021 Feb 23.
Published in final edited form as: Green Chem. 2019 Oct 29;21(23):6246–6251. doi: 10.1039/C9GC03161H

Table 3. Overall yields for the multi-enzymatic conversion [%] of 1 (trans or cis) into 1R,2R-5 or 1S,2R-5 .

Entry Sub. Step 1
Yield [%]		 Step 2
Yield [%]		 Combined
Yield [%]		 er [%] dr [%]
1 trans-1 85 74 63 (1S,2R-5) >99.5 : <0.5 98 : 2a
2 cis-1 79 74 59 (1R,2R-5) >99.5 : <0.5 >99.5 : <0.5
a

Dependent on stereoselectivity of Step 1.