Extended Data Table 1. Antibody used in this study.
| Target | Application | Reference | Quantity |
| γH2AX(S139) | ChIP | Merck Millipore 07-164 | 2 μg |
| γH2AX (S139) | IF | Merck Millipore 05-636 (clone JBW301) | 1:1000 |
| P-ATM (S1981) | ChIP | Abeam ab81292 | 2 μg |
| MDC1 | ChIP | Abeam ab11171 | 3 μg |
| SCC1 | ChIP | Abeam ab992 | 4 μg |
| SCC1 | Western Blot | Abeam ab992 | 1:500 |
| WAPL | Western Blot | Santa Cruz sc-365189 | 1:500 |
| NIPBL | Western Blot | Bethyl Laboratories A301-779A | 1:1000 |
| MRE11 | Western Blot | GeneTex GTX70212 (clone 12D7) | 1:4000 |
| Tubulin | Western Blot | Sigma T6199 | 1:10000 |
| Myosin | Western Blot | Sigma M3567 | 1:2000 |
| Phospho-CHK1 (ser345) | Western Blot | Cell Signaling 2348S | 1:1000 |
| P-SMC1 (S966) | ChIP | Epitomics EP2858Y | 2 μL |
| P-SMC3 (S1083) | ChIP | Bethyl Laboratories A300-480A | 2 μg |
| CTCF | ChIP | Millipore 07-729 | 4 μL |
| γH2A (yeast) | ChIP | Abeam ab15083 | 2μg |