Extended Data Fig. 6. Functional assays reveal normal homing of CD22 mutant B cells to the spleen and bone marrow.
Localization of WT, Cd22 –/–, CD22Y2,5,6F, and CD22R130E B cells in blood, spleen and bone marrow (BM) after homing assays as illustrated in Fig. 6c. Data are shown as a percentage of the mean localization ratio of the WT group. Shown are pooled data (mean ± SEM) of n=3-5 experiments with 11-16 mice per group total.