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. Author manuscript; available in PMC: 2021 Jul 18.
Published in final edited form as: Nat Ecol Evol. 2021 Jan 18;5(3):369–378. doi: 10.1038/s41559-020-01371-2

Extended Data Fig. 3. CpH methylation is specific to brain tissues across vertebrates.

Extended Data Fig. 3

Sequence motifs found surrounding the highest methylated CpH positions in each sample. CpH positions were required to have a coverage ≥ 10x. hpf = embryo hours post fertilization. Sox10+ cells correspond to developmental neural crest cells in zebrafish. (b) Gene Ontology enrichments for genes showing the highest and lowest gene body methylation levels in the CpA context, as defined by belonging to the top and bottom deciles in each species and tissue. (c) Gene Ontology enrichments for genes showing the highest and lowest methylated levels in the CpG context.