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. Author manuscript; available in PMC: 2021 Jul 18.
Published in final edited form as: Nat Ecol Evol. 2021 Jan 18;5(3):369–378. doi: 10.1038/s41559-020-01371-2

Extended Data Fig. 4. Anticorrelation between CpG and CpA methylation and transcription is restricted to a subset of vertebrate samples.

Extended Data Fig. 4

Distribution of gene body methylation levels on genes separated by expression level on brain tissue. “No expression” category includes all genes with TPM < 1, whereas the rest of genes were classified in 10 deciles of expression (lower expression left, higher expression right). Positive correlation between expression and CpG methylation is restricted to invertebrate brain samples. Boxplot centre lines are medians, box limits are quartiles 1 (Q1) and 3 (Q3), whiskers are 1.5 × interquartile range (IQR).