Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Aug 28;354(2):263–271. doi: 10.1016/j.canlet.2014.08.022

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Fig. 5 — BAG3 down-modulation and PEITC restore p53 levels in HeLa cells. (A) p53 levels in control (Ctrl), scrRNA (scr)- and BAG3siRNA (siRNA)-transfected HeLa cells harvested at 72 h post-transfection. Eighty micrograms of proteins were loaded in each lane. Data are expressed as p53/GAPDH densitometry ratios and represented as the mean values ± SD from at least three experiments (**p < 0.001). BAG3 silencing was checked. (B) p53 mRNA levels by qRT-PCR. p53 mRNA levels (Y axis) in scrRNA (scr) and BAG3siRNA (siRNA) are expressed relative to p53 mRNA level in control cells. Data are the mean values ± SD from two independent experiments performed in duplicate. (C) Effect of BAG3 silencing on p53 levels in C33A cells. (D) BAG3 and p53 levels in C33A and HeLa cells exposed to 20 µM PEITC for 10 h. The blots in C and D are from one experiment representative of at least two with similar results.