Skip to main content
. 2019 Aug 1;166:4–18. doi: 10.1016/j.biochi.2019.07.026

Table 8.

Other peptidase families possibly present in LUCA. The following peptidase families are present in all kingdoms but not found within most phyla in some kingdoms. These may have been present in LUCA and subsequently lost in some phyla.

Family Type example Kingdoms with few represented phyla
C26 gamma-glutamyl carboxypeptidase Chromista
C44 amidophosphoribosyltransferase precursor Fungi, Chromista
M14 carboxypeptidase A Archaea
M16 pitrilysin Archaea
M28 aminopeptidase Y Chromista
M38 beta-aspartyl dipeptidase Fungi
M50 S2P endopeptidase Fungi
M79 RCE1 peptidase Fungi
S15 Xaa-Pro dipeptidyl peptidase Animalia, Viridiplantae (absent from Streptophyta), Fungi, Chromista, Protozoa
S33 prolyl aminopeptidase Chromista
T2 asparaginase Protozoa
T3 gamma glutamyl transpeptidase Protozoa, Archaea