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Hepatic atrophy in a PCV2-infected non-immunostimulated pig. Immunohistochemical staining of a section of liver which demonstrates the distribution of the capsid structural protein of PCV2 in the liver of a PMWS-affected pig. Viral antigen is present in the cytoplasm of Kupffer cells and infiltrating macrophages (arrows) as both multiple viral inclusion bodies and as diffusely distributed cytoplasmic product. Hepatocytes are largely devoid of viral antigen.
