Fig. 3.

Cytokine production by immature and mature Mo-DCs treated with SHXB and STC3, and T cell activation stimulated by the virulent SHXB- and STC3-infected immature and mature Mo-DCs.

(A) Bar graphs show the production of three cytokines in immature Mo-DCs infected with SHXB and STC3, including Interleukin-12 (left), Interferon-γ (middle) and Interleukin-10 (right). (B) SHXB- and STC3-infected immature and mature Mo-DCs (24 h p.i.) were co-cultured with T lymphocytes (ratios 1:1, 1:10 and 1:100). Five days after infection, co-culture proliferation was evaluated using CFSE. Data represent the mean ± SEM (n = 3). Bars showing different letters represent values significantly different from each other (P < 0.05).