Table 4.

Comparison of the amino acid sequences of spike proteins in CRCoV and BCoV strains.

Virus	Clinical forms	Strain, clone or isolate	Country	Accession No.	Host	Amino acid at residue
						40	101	103	118	235	407	440	492	528	540	582	695	744	828	887	933	1069	1256	1257	1289
CRCoV	Respiratory infection	K9a	Korea	EU983105	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
		K37	Korea	EU983106	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
		K39	Korea	EU983107	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
		4182	UK	DQ682406	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
		240-05	Italy	EU999954	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
		T101	UK	AY150272	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
		02/005	Japan	AB242262	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
		06/075	Japan	AB370269	Dog	V	D	V	V	H	M	I	N	N	L	K	S	S	V	F	D	A	L	M	H
BCoV	Respiratory	LSU-94		AF058943	Cow	T	N	I	K	N	L	V	D	A	T	Q	A	V	A	V	E	S	S	V	Q
	Enteritis	LY-138		AF058942	Cow	T	N	I	M	N	L	V	D	A	T	Q	A	A	A	V	E	S	S	V	Q
	Winter dysentery	KWD2		AY935638	Cow	T	N	I	M	N	L	V	D	A	T	Q	A	V	A	V	E	S	S	V	Q
	Summer dysentery	339/06		EF445634	Cow	T	N	I	M	N	L	V	D	A	T	Q	A	V	A	V	E	S	S	V	Q
	Calf diarrhea	KCD8		DQ389639	Cow	T	N	I	M	N	L	V	D	A	T	Q	A	V	A	V	E	S	S	V	Q
	Avirulent	Mebus		U00735	Cow	I	N	I	M	N	L	V	D	A	T	Q	A	V	A	V	E	S	S	V	Q

^aThe three CRCoV strains isolated from dogs in Korea are in bold.