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. 2008 Dec 11;137(1):10–17. doi: 10.1016/j.vetmic.2008.12.007

Table 1.

Neutralizing antibody titers in immunized guinea pigs.

Time Guinea pigs (no.) Neutralizing antibodies titera
Group A Group B Group C
0 dpv 1 <0.6 <0.6 <0.6
2 <0.6 <0.6 <0.6
3 <0.6 <0.6 <0.6
14 dpv (primary) 1 0.9 0.9 <0.6
2 1.5 0.75 <0.6
3 1.2 0.9 <0.6
28 dpv (primary) 1 0.9 0.9 <0.6
2 1.8 1.2 <0.6
3 2.1 1.2 <0.6
14 dpv (boosted) 1 1.5 1.5 <0.6
2 2.1 1.5 <0.6
3 2.1 1.5 <0.6
28 dpv (boosted) 1 1.8 1.2 <0.6
2 1.5 1.5 <0.6
3 2.1 1.2 <0.6

Neutralizing antibody determinations were performed with sera sampled at day 0 (prior to vaccination), day 14 and day 28 after the primary and booster vaccinations. Serum samples were obtained from three guinea pigs from each group. dpv: days post vaccination.

a

Log10 reciprocal antibody titers to neutralize 100 TCID50 of homologous FMDV in 50% of the wells.