Table 4.
Histology and immunohistochemistry analysis of intestinal infected with PDCoV strain CHN-HN-2014.
| Group | Pig ID | VH: CD, mean (±SD)* | Antigen detection in the intestinal† |
||
|---|---|---|---|---|---|
| Duodenum | Jejunum | Ileum | |||
| challenged | 1 | 2.9 (0.6) | + | +++ | ++ |
| 8 | 3.8 (1.1) | + | +++ | ++ | |
| control | 9 | 6.1 (0.7) | – | – | – |
| 11 | 5.6 (0.3) | – | – | – | |
*
VH: CD, ratio of villous height to crypt depth.
†
Antigen detection by immunohistochemical staining: +, 1%–30% of epithelial cells showed staining; ++, 31%–60% of epithelial cells showed staining; +++, 61%–100% of epithelial cells showed staining;-,no epithelial cells showed staining.