Table 4.
Mutated amino acids that cannot be explained by a single-base change in RNA codons
| Protein | Position | Mutation | Change in 2 RNA codes | Change in 3 RNA codes |
|---|---|---|---|---|
| BTK | 594 | Glycine → glutamine | GGG → CAG | |
| OC43 | 29 | Lysine → valine | AAA → GUA | |
| 173 | Glutamine → asparagine | CAA → AAU | ||
| AAC | ||||
| 603 | Leucine → threonine | CUU → ACU | ||
| 630 | Leucine → threonine | UUA → ACA | ||
| 896 | Glutamic acid → cysteine | GAA → UGU | ||
| UGG | ||||
| 912 | Aspartic acid → serine | GAU → UCU | ||
| AGU | ||||
| p53 | 140 | Threonine → tyrosine | ACC → UAC | |
| 157 | Valine → serine | GUC → UCC | ||
| AGC | ||||
| 174 | Arginine → histidine | AGG → CAU | ||
| CAC | ||||
| 247 | Asparagine → tryptophan | AAC → UGG | ||
| PH4H | 157 | Arginine → asparagine | AGA → AAU | |
| AAC | ||||
| VHL | 70 | Glutamic acid → leucine | GAG → UUG | |
| CUG | ||||
| 101 | Leucine → glycine | CUG → GGG | ||
| 115 | Histidine → glutamic acid | CAC → GAA | ||
| GAG | ||||
| 157 | Threonine → aspartic acid | ACU → GAU |
BTK, Bruton’s tyrosine kinase; OC43, human coronavirus OC43; p53, human p53 protein; PH4H, phenylalanine hydroxylase protein; VHL, von Hippel–Lindau disease tumor suppressor.