Table 2.
Summary of reproductive record and pathological lesions of sows experimentally infected with Virus X isolate ISUYP604671 at early gestation
| Sows (inoculum) | Average # of litter in previous gestations | No. of fetuses recovered at necropsy | Significant gross lesionsa | Significant microscopic lesionsa | Recovery of Virus X from sow/fetus |
|---|---|---|---|---|---|
| 800 (serum) | 11.4 | 3 | Yes | Yes | Yes/Yes |
| 21622 (virus isolate-P2) | 13.3 | 0 | No | No | Yes/NAb |
| 30021 (virus isolate-P3) | 11.2 | 13 | No | No | Yes/Yes |
| 30172 (virus isolate-P1) | 8.4 | 10 | Yes | Yes | Yes/Yes |
| 30120 (sham inoculum) | 10.2 | 6 | No | No | No/No |
The virus inocula were prepared at various cell passages (P).
a
Significant gross lesions were hemorrhages in inguinal lymph node, decolorization of uterus (green and brown) and possible embryonic death of fetuses. Microscopically, necrotic edema in the lymph node, mineralization plaques in uterus and necrotic debris in the lumen were observed.
b
NA: not applicable.