Fig. 1.

Evaluation of the replication of icPC22A and icPC22A-S1Δ197 in Gn pigs infected with individual or both viruses. (A) Fecal consistency scores of individual Gn piglets and the mean of each group were shown. The scores were named as follows: 0, solid (normal); 1, pasty (normal); 2, semiliquid (mild diarrhea); and 3, liquid (severe diarrhea). Two piglets from icPC22A, icPC22A-S1Δ197 and coinfection groups, and one pig from mock group were euthanized at 12 hpi and 2–3 dpi, respectively, for histopathological examination. (B) Fecal PEDV N gene RNA shedding titers (for both icPC22A and icPC22A-S1Δ197) of each group. Data are shown as mean (M) ± standard deviations (SD) of pigs in each group. (C) Fecal PEDV S gene RNA shedding titles of each virus. Data are shown as M ± SD.