Table 2. . Combination testing of fosfomcyin–meropenem and fosfomcyin–colistin against carbapenemase producing K. pneumoniae using time-kill assay.
Carbapenem resistant genes (n) | Fosfomcyin–meropenem | Fosfomcyin–colistin | ||
---|---|---|---|---|
Synergy, n (%) | Indifference, n (%) | Synergy, n (%) | Indifference, n (%) | |
blaOXA-48.like (n = 34) | 8 (24) | 26 (76) | 5 (15) | 29 (85) |
blaNDM (n = 11) | 1 (9) | 10 (91) | 2 (18) | 9 (82) |
blaOXA-48.like + blaNDM (n = 5) | 1 (20) | 4 (80) | 1 (20) | 4 (80) |