Table 1.
Published proteome microarrays
Organism | Published year/PI | Proteins | Applications |
---|---|---|---|
Expression based | |||
Yeast | 2001/M. Snyder [5] | 5800 | Interactions: protein–protein, protein–phospholipids [5]; protein–DNA [53]; phosphorylation network [30]; glycosylation [6,27]. |
2005/M. Snyder [27] | 5854 | ||
Arabidopsis | 2005/B. Kersten [19] | 1690 | Phosphorylation [19]; protein–protein interaction [54,55]; PDI/transcriptional network [56]. |
2007/S.P. Dinesh-Kumar [54,55] | 1133 | ||
2008/X.W. Deng [56] | 802 | ||
SARS -CoV | 2006/M. Snyder [57] | 100% of SARS-CoV and the majority of five other CoVs | Serum biomarker identification for SARS-CoV diagnostics [57]. |
E. coli | 2008/H. Zhu [20] | 4256 | DNA repair protein identification [20]; inflammation bowel disease (IBD) biomarker screening [58]. |
Human | 2005/ProtoArray® V1.0 | >1000 | Serum profiling [59]; kinase substrate and inhibitor screening [60]; ubiquitination and sumoylation [61]. |
2010/ProtoArray® V5.0 | >9000 | ||
IVTT based | |||
Vaccinia | 2005/P.L. Felgner [32,33] | 185 | Serum biomarker identification for diagnostics and vaccination. |
E. coli | 2006/H. Yanagawa [62] | 4337 | Protein–protein interaction. |
Francisella tularensis | 2007/P.L. Felgner [63] | 1741 | Serum biomarker identification for diagnostics and vaccination. |
Coxiella burnetii | 2008/P.L. Felgner [64] | 1988 | Serum biomarker identification for diagnostics and vaccination. |
P. falciparum | 2008/P.L. Felgner [65] | 250 | Serum biomarker identification for diagnostics and vaccination. |
Burkholderia pseudomallei | 2009/P.L. Felgner [66] | 1205 | Serum biomarker identification for diagnostics and vaccination. |
Chlamydia trachomatis | 2010/L.M. de la Maza [67] | 225 | Serum biomarker identification for diagnostics and vaccination. |
C. albicans | 2010/H.P. Liu [35] | 336 | Serum biomarker identification for diagnostics and vaccination. |
Brucella melitensis | 2010/P.L. Felgner [68] | 1406 | Serum biomarker identification for diagnostics and vaccination. |
M. tuberculosis | 2010/M.L. Gennaro [34] | 4099 | Serum biomarker identification for diagnostics and vaccination. |