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. 2011 Jan 21;43(3):161–171. doi: 10.1093/abbs/gmq127

Table 1.

Published proteome microarrays

Organism Published year/PI Proteins Applications
Expression based
 Yeast 2001/M. Snyder [5] 5800 Interactions: protein–protein, protein–phospholipids [5]; protein–DNA [53]; phosphorylation network [30]; glycosylation [6,27].
2005/M. Snyder [27] 5854
 Arabidopsis 2005/B. Kersten [19] 1690 Phosphorylation [19]; protein–protein interaction [54,55]; PDI/transcriptional network [56].
2007/S.P. Dinesh-Kumar [54,55] 1133
2008/X.W. Deng [56] 802
 SARS -CoV 2006/M. Snyder [57] 100% of SARS-CoV and the majority of five other CoVs Serum biomarker identification for SARS-CoV diagnostics [57].
E. coli 2008/H. Zhu [20] 4256 DNA repair protein identification [20]; inflammation bowel disease (IBD) biomarker screening [58].
 Human 2005/ProtoArray® V1.0 >1000 Serum profiling [59]; kinase substrate and inhibitor screening [60]; ubiquitination and sumoylation [61].
2010/ProtoArray® V5.0 >9000
IVTT based
Vaccinia 2005/P.L. Felgner [32,33] 185 Serum biomarker identification for diagnostics and vaccination.
E. coli 2006/H. Yanagawa [62] 4337 Protein–protein interaction.
Francisella tularensis 2007/P.L. Felgner [63] 1741 Serum biomarker identification for diagnostics and vaccination.
Coxiella burnetii 2008/P.L. Felgner [64] 1988 Serum biomarker identification for diagnostics and vaccination.
P. falciparum 2008/P.L. Felgner [65] 250 Serum biomarker identification for diagnostics and vaccination.
Burkholderia pseudomallei 2009/P.L. Felgner [66] 1205 Serum biomarker identification for diagnostics and vaccination.
Chlamydia trachomatis 2010/L.M. de la Maza [67] 225 Serum biomarker identification for diagnostics and vaccination.
C. albicans 2010/H.P. Liu [35] 336 Serum biomarker identification for diagnostics and vaccination.
Brucella melitensis 2010/P.L. Felgner [68] 1406 Serum biomarker identification for diagnostics and vaccination.
M. tuberculosis 2010/M.L. Gennaro [34] 4099 Serum biomarker identification for diagnostics and vaccination.