TABLE 2.
Levels of the antibiotics in the blood after i.p. administration
Blood | Hour 8 | Hour 24 | Hour 48 | Hour 72 | p* | p-values of paired comparisons | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
I–II | I–III | I–IV | II–III | II–IV | III–IV | ||||||
Doripenem | 0.30 (0.14–0.36) | 0.21 (0.17–0.32) | 0.21 (0.18–0.28) | 0.21 (0.18–0.31) | 0.796 | ||||||
Moxifloxacin | 1.23 (1.01–1.35) | 0.39 (0.18–0.52) | 0.17 (0.11–0.25) | 0.14 (0.08–0.31) | 0.014 | 0.046 | 0.028 | 0.027 | 0.015 | 0.207 | 0.623 |
P-values for the changes of the variables in time.