Table 1.
Girls (N=165) |
Boys (N=208) |
||||
---|---|---|---|---|---|
LOQ | n<LOQ (%) | Median (5th, 95th percentile) a | n<LOQ (%) | Median (5th, 95th percentile) a | |
Serum-PFHxS | 0.03 ng/mL | 0% | 0.30 (0.15, 0.66) | 0.5% | 0.34 (0.13, 0.69) |
Serum-PFOS | 0.03 ng/mL | 0% | 8.07 (4.21, 15.50) | 0% | 8.33 (4.09, 15.67) |
Serum-PFOA | 0.03 ng/mL | 0% | 1.70 (0.67, 3.70) | 0% | 1.64 (0.73, 3.76) |
Serum-PFNA | 0.03 ng/mL | 0% | 0.66 (0.38, 1.43) | 0% | 0.67 (0.36, 1.40) |
Serum-PFDA | 0.03 ng/mL | 0% | 0.26 (0.16, 0.45) | 0% | 0.26 (0.14, 0.51) |
DHEA | 0.88 nM | 0% | 4.97 (2.23, 13.69) | 0.5% | 4.50 (1.65, 12.32)* |
DHEAS | 48 nM | 7.9% | 173.59 (24.00, 622.65) | 7.7% | 161.81 (24.00, 585.06) |
Androstenedione | 0.18 nM | 13.9% | 0.33 (0.09, 0.75) | 19.7% | 0.31 (0.09, 0.65)* |
17-OHP | 0.19 nM | 0.6% | 0.95 (0.38, 2.52) | 0.5% | 1.23 (0.46, 2.66)* |
Testosterone | 0.10 nM | 83.6% | 0.05 (0.05, 0.14) | 1.4% | 3.23 (0.43, 8.32)* |
LH | 0.05 IU/L | 0% | 0.15 (0.05, 1.12) | 0% | 2.00 (0.54, 5.28)* |
FSH | 0.10 IU/L | 0% | 4.56 (2.15, 12.10) | 0% | 1.45 (0.56, 2.96)* |
Note: Data are presented as median (5th, 95th percentile).
17-OHP, 17-hydroxyprogesterone; DHEA, dehydroepiandrosterone; DHEAS, Dehydroepiandrosterone-sulfate, FSH, Follicle-Stimulating Hormone; LH, luteinizing hormone; LOQ, Limit of Quantification, PFDA, Perfluorodecanoic acid; PFHxS, Perfluorohexane sulfonic acid; PFOS, Perfluorooctane sulfonic acid; PFOA, Perfluorooctanoic acid; Perfluorooctane sulfonic acid; PFNA, Perfluorononanoic acid.
Values below limit of quantification (LOQ) were substituted by LOQ/2.
p-value<0.05, when comparing PFAA concentrations and hormone concentration between boys and girls using Wilcoxon rank sum test.