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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Environ Res. 2019 Dec 31;182:109101. doi: 10.1016/j.envres.2019.109101

Table 1.

Maternal pregnancy serum PFAA and serum androgens, androgen precursors, and gonadotropins concentrations in infants at four months of age

Girls (N=165)
Boys (N=208)
LOQ n<LOQ (%) Median (5th, 95th percentile) a n<LOQ (%) Median (5th, 95th percentile) a
Serum-PFHxS 0.03 ng/mL 0% 0.30 (0.15, 0.66) 0.5% 0.34 (0.13, 0.69)
Serum-PFOS 0.03 ng/mL 0% 8.07 (4.21, 15.50) 0% 8.33 (4.09, 15.67)
Serum-PFOA 0.03 ng/mL 0% 1.70 (0.67, 3.70) 0% 1.64 (0.73, 3.76)
Serum-PFNA 0.03 ng/mL 0% 0.66 (0.38, 1.43) 0% 0.67 (0.36, 1.40)
Serum-PFDA 0.03 ng/mL 0% 0.26 (0.16, 0.45) 0% 0.26 (0.14, 0.51)
DHEA 0.88 nM 0% 4.97 (2.23, 13.69) 0.5% 4.50 (1.65, 12.32)*
DHEAS 48 nM 7.9% 173.59 (24.00, 622.65) 7.7% 161.81 (24.00, 585.06)
Androstenedione 0.18 nM 13.9% 0.33 (0.09, 0.75) 19.7% 0.31 (0.09, 0.65)*
17-OHP 0.19 nM 0.6% 0.95 (0.38, 2.52) 0.5% 1.23 (0.46, 2.66)*
Testosterone 0.10 nM 83.6% 0.05 (0.05, 0.14) 1.4% 3.23 (0.43, 8.32)*
LH 0.05 IU/L 0% 0.15 (0.05, 1.12) 0% 2.00 (0.54, 5.28)*
FSH 0.10 IU/L 0% 4.56 (2.15, 12.10) 0% 1.45 (0.56, 2.96)*

Note: Data are presented as median (5th, 95th percentile).

17-OHP, 17-hydroxyprogesterone; DHEA, dehydroepiandrosterone; DHEAS, Dehydroepiandrosterone-sulfate, FSH, Follicle-Stimulating Hormone; LH, luteinizing hormone; LOQ, Limit of Quantification, PFDA, Perfluorodecanoic acid; PFHxS, Perfluorohexane sulfonic acid; PFOS, Perfluorooctane sulfonic acid; PFOA, Perfluorooctanoic acid; Perfluorooctane sulfonic acid; PFNA, Perfluorononanoic acid.

a

Values below limit of quantification (LOQ) were substituted by LOQ/2.

*

p-value<0.05, when comparing PFAA concentrations and hormone concentration between boys and girls using Wilcoxon rank sum test.