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. Author manuscript; available in PMC: 2020 Apr 2.
Published in final edited form as: Oral Oncol. 2019 May 17;94:47–57. doi: 10.1016/j.oraloncology.2019.05.006

Table 1 –

Distribution of cases of oral and pharyngeal cancer, laryngeal cancer, and controls according to selected variables. INHANCE consortium

Controls (%) Oral and pharyngeal cancer cases (%) Laryngeal cancer cases (%)
29,844 13,317 4,943
Sexa
Female 9,599 (32) 3,786 (28) 730 (15)
Male 20,245 (68) 9,531 (72) 4,213 (85)
Age (years)a
<40 2,063 (7) 708 (5) 94 (2)
40 to 44 2,045 (7) 823 (6) 207 (4)
45 to 49 3,018 (10) 1,692 (13) 471 (10)
50 to 54 4,231 (14) 2,321 (17) 787 (16)
55 to 59 5,044 (17) 2,627 (20) 1,025 (21)
60 to 64 4,726 (16) 2,185 (16) 1,011 (20)
65 to 69 4,181 (14) 1,489 (11) 754 (15)
70 to 74 3,044 (10) 922 (7) 413 (8)
≥75 1,492 (5) 550 (4) 181 (4)
Racea
White 21,462 (72) 9,076 (68) 3,627 (73)
Black 976 (3) 683 (5) 169 (3)
Hispanic 421 (1) 149 (1) 41 (1)
Asian and Pacific Islanders 3,849 (13) 1,293 (10) 77 (2)
Others and Brazilians 3,136 (11) 2,116 (16) 1,029 (21)
Study
Aviano 802 (3) 288 (2) 128 (3)
Baltimore 163 (1) 123 (1) 29 (1)
Beijing 377 (1) 322 (2) 0 (0)
Boston 473 (2) 339 (3) 75 (2)
Buffalo 863 (3) 282 (2) 113 (2)
Central Europe 730 (2) 238 (2) 295 (6)
France Multicen. (1989–1991) 255 (1) 163 (1) 247 (5)
France Multicen. (2001–2007) 2,964 (10) 1,343 (10) 366 (7)
Germany-Heidelberg 644 (2) 0 (0) 172 (3)
Germany-Saarland 83 (0) 53 (0) 22 (0)
HOTSPOT 59 (0) 63 (0) 0 (0)
Houston 738 (2) 561 (4) 119 (2)
International Multicenter 1,450 (5) 1,053 (8) 0 (0)
Iowa 600 (2) 344 (3) 58 (1)
Italy Multicenter 2,506 (8) 685 (5) 421 (9)
Japan (2001–2005) 2,817 (9) 392 (3) 71 (1)
Latin America 1,446 (5) 981 (7) 612 (12)
Los Angeles 905 (3) 273 (2) 70 (1)
Milan (1984–1989) 1,413 (5) 161 (1) 215 (4)
Milan (2006–2009) 669 (2) 118 (1) 162 (3)
MSKCC 115 (0) 61 (0) 20 (0)
New York Multicenter 1,246 (4) 818 (6) 202 (4)
North Carolina (1994–1997) 154 (1) 91 (1) 31 (1)
North Carolina (2002–2006) 982 (3) 594 (4) 283 (6)
Puerto Rico 410 (1) 182 (1) 0 (0)
Rome 350 (1) 98 (1) 173 (3)
Sao Paulo 1,519 (5) 1,042 (8) 406 (8)
Seattle (1985–1995) 465 (2) 317 (2) 0 (0)
Seattle-Leo 371 (1) 264 (2) 123 (2)
Switzerland 824 (3) 311 (2) 104 (2)
Tampa 789 (3) 115 (1) 48 (1)
US Multicenter 936 (3) 710 (5) 0 (0)
Western Europe 1,726 (6) 932 (7) 378 (8)
Educationa
No education 1,078 (4) 726 (5) 118 (2)
≤Junior high school 10,456 (35) 4,674 (35) 2,371 (48)
Some high school 5,330 (18) 2,751 (21) 922 (19)
High school graduate 3,883 (13) 1,883 (14) 717 (14)
Technical school, some college 4,825 (16) 1,989 (15) 496 (10)
≥College graduate 4,272 (14) 1,294 (10) 319 (6)
Drinking status
Never user 8,068 (27) 2,279 (17) 578 (12)
Former user 3,072 (10) 2,521 (19) 833 (17)
Current user 14,210 (48) 6,943 (52) 2,442 (49)
Missing 4,494 (15) 1,574 (12) 1,091 (22)
Alcohol drinking intensity (number of drinks/day)
0-<1 17,207 58) 4,899 37) 1,433 (29)
1-<5 8,913 30) 4,099 31) 1,757 (35)
≥5 2,925 10) 3,814 29) 1,626 (33)
Missing 799 3) 505 4) 127 (3)
Alcohol duration (years)
Never drinkers 8,068 (27) 2,279 (17) 578 (12)
0-<20 2,984 (10) 1,182 (9) 297 (6)
20-<40 9,427 (32) 5,422 (41) 1,848 (37)
40-<60 6,013 (20) 2,920 (22) 1,435 (29)
≥60 412 (1) 176 (1) 123 (2)
Missing 2,940 (10) 1,338 (10) 662 (13)

ABBREVIATIONS: MSKCC: Memorial Sloan Kettering Cancer Center.

a

We excluded subjects with missing information on age, sex, and race (see Figure 1). Missing values for education were imputed according to the INHANCE protocol.11