Table 1.
Demographic, environmental, and reproductive information on study participants.
| All PM | FXPOI | No FXPOI | |
|---|---|---|---|
| N | 355 | 87 | 168 |
| Age at interview | 47.4 ± 12.5 | 46.2 ± 10.6 | 53.5 ± 8.8a |
|
Mean ± SD (min–max) |
(19–93) | (26–72) | (37–80) |
| Race | |||
| % White | 90.4 | 93.1 | 88.7 |
| % Black | 3.7 | 2.3 | 4.8 |
| % Hispanic | 3.9 | 2.3 | 4.8 |
| % Other | 2.0 | 2.3 | 1.7 |
| Body mass index (BMI) |
27.4 ± 6.8 (17.4–63.4) |
27.6 ± 6.8 (17.5–49.9) |
28.0 ± 6.4 (18.2–55.0) |
| % Ever smoked | 27.7 | 24.1 | 29.3 |
| Number of children | 1.7 ± 1.3 | 1.6 ± 1.2 | 2.0 ± 1.1b |
|
Mean ± SD (Min–max) |
(0–8) | (0–5) | (0–6) |
| Number of children with FXS | 0.8 ± 0.8 | 0.7 ± 0.8 | 0.8 ± 0.7 |
|
Mean ± SD (Min–max) |
(0–3) | (0–2) | (0–3) |
| % Satisfied with number of children | 78.7 | 65.5 | 88.1c |
| Number of conditions: mean ± SD; median; mode (min–max) |
4.0 ± 3.5; 3; 1 (0–16) |
4.4 ± 4.0; 3; 1 (0–16) |
3.9 ± 3.4; 3; 0 (0–15) |
| Repeat size | |||
|
Mean ± SD (Min–max) |
91.9 ± 19.4 (56–190) |
89.6 ± 14.2 (56–140) |
91.7 ± 20.7 (56–190) |
| % 55–79 | 25.0% | 19.8% | 28.1%d |
| % 80–100 | 49.4% | 61.6% | 44.5% |
| % 101–200 | 25.6% | 18.6% | 27.4% |
FXPOI fragile X–associated primary ovarian insufficiency, FXS fragile X syndrome, PM premutation.
ap < 0.0001 using a t-test to compare means among women with and without FXPOI.
bp < 0.05 using a t-test to compare means among women with and without FXPOI.
cp < 0.0001 using chi-square analysis to compare frequencies among women with and without FXPOI.
dp < 0.05 using chi-square analysis to compare frequencies among women with and without FXPOI.