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. 2020 Jan 3;22(4):758–766. doi: 10.1038/s41436-019-0733-5

Table 2.

Frequency of reported conditions for all women with a PM, those with FXPOI, and those without FXPOI, listed in order of frequency reported by all PM women.

All PM (N = 355) FXPOI (N = 87) No FXPOI (N = 168) P values for models comparing FXPOI and no FXPOIc
% Total % Option 1a /% option 2b % Total % Option 1a /% option 2b % Total % Option 1a /% option 2b Model 1: logistic regression Model 2: logistic regression Survival analysis
Anxiety 37.8% 15.2% / 22.5% 44.8% 12.6% / 32.2% 30.4% 12.5% / 17.9% 0.161 0.150 0.001
Depression 35.5% 8.4% / 27.0% 33.3% 2.3% / 31.0% 35.1% 10.1% / 25.0% 0.412 0.541 0.044
Migraine headaches 33.2% 12.4% / 20.8% 33.3% 9.2% / 24.1% 26.8% 8.3% / 18.4% 0.809 0.485 0.087
Tension headaches 31.5% 21.7% / 9.9% 31.0% 17.2% / 13.8% 28.6% 22.0% / 6.5% 0.671 0.098 0.026
Sleep problems 28.7% 20.8% / 7.9% 34.5% 26.4% / 8.0% 30.4% 21.4% / 8.9% 0.249 0.914 0.608
Peripheral neuropathy 20.3% 14.7% / 5.6% 22.1% 16.3% / 5.8% 21.4% 14.3% / 7.1% 0.802 0.811 0.899
IBS 19.7% 8.2% / 11.5% 19.5% 6.9% / 12.6% 17.9% 8.3% / 9.5% 0.613 0.710 0.201
Osteoporosis 19.1% 1.4% / 17.7% 26.4% 0% / 26.4% 20.8% 1.8% / 19.0% 0.017 0.056 0.001
Hypothyroidism 17.5% 3.1% / 14.4% 23.0% 2.3% / 20.7% 17.9% 3.0% / 14.9% 0.221 0.114 0.033
Hypertension 16.9% 0.6% / 16.3% 10.3% 1.1% / 9.2% 23.8% 0% / 23.8% 0.130 0.074 0.170
RLS 15.2% 11.3% / 3.9% 12.6% 9.2% / 3.4% 14.9% 11.3% / 3.6% 0.895 0.544 0.381
Ataxia 13.5% 9.9% / 3.7% 9.2% 5.7% / 3.4% 15.5% 11.3% / 4.2% 0.799 0.578 0.562
Sleep apnea 13.0% 5.6% / 7.3% 14.9% 6.9% / 8.0% 16.7% 6.5% / 10.1% 0.870 0.719 0.460
Chronic muscle pain 11.9% 7.3% / 4.5% 14.9% 5.7% / 9.2% 10.1% 7.1% / 3.0% 0.125 0.027 0.025
Social phobia 11.8% 10.7% / 1.1% 20.7% 18.4% / 2.3% 10.7% 9.5% / 1.2% 0.025 0.462 0.370
Fibromyalgia 11.5% 4.5% / 7.0% 16.1% 3.4% / 12.6% 9.5% 4.8% / 4.8% 0.100 0.019 0.005
CFS 11.3% 9.0% / 2.2% 14.9% 11.5% / 3.4% 8.3% 6.5% / 1.8% 0.083 0.382 0.201
TMJ 11.3% 1.4% / 9.9% 16.0% 4.6% / 11.5% 10.7% 0% / 10.7% 0.170 0.846 0.473
OCD 10.7% 8.4% / 2.2% 10.3% 5.7% / 4.6% 11.9% 9.5% / 2.4% 0.288 0.980 0.228
ADHD 10.7% 7.6% / 3.1% 12.6% 10.3% / 2.3% 10.1% 6.5% / 3.6% 0.974 0.289 0.736
LD 10.4% 7.6% / 2.8% 6.9% 5.7% / 1.1% 10.7% 8.3% / 2.4% 0.347 0.124 0.589
Tremor 10.1% 7.0% / 3.1% 8.0% 5.7% / 2.3% 11.9% 8.3% / 3.6% 0.811 0.823 0.806

Model 1: endorsement of either option 1 or option 2 was used to define affected individuals. Model 2: endorsement of option 2 only is used to define affected individuals. Endorsement of option 1 is grouped with option 0 as the unaffected population.

ADHD attention deficit–hyperactivity disorder, CFS chronic fatigue syndrome, IBS irritable bowel syndrome, LD learning disability, OCD obsessive compulsive disorder, RLS restless leg syndrome, TMJ temporomandibular joint dysfunction.

a% of subjects who selected “I think I have this but have not been diagnosed by a medical professional.”

b% of subjects who selected “I have been diagnosed with this by a medical professional.”

cBonferroni-adjusted statistical significance p < 0.002 are bolded; Marginally significant models where significance was between 0.001 and 0.05 are underlined.