Table 3.
Associations of demographic, environmental, and reproductive variables with number of conditions reported.
| Sample size in model | β coefficient | R2 | p valuea | |
|---|---|---|---|---|
| Mean age | 354 | 0.026 | 0.01 | 0.0810 |
| BMI | 352 | 0.128 | 0.06 | <0.0001 |
| Ever smoked (y/n) | 354 | 1.779 | 0.05 | <0.0001 |
| Number of children | 355 | 0.371 | 0.02 | 0.0120 |
| Number of children with FXS | 348 | 0.380 | 0.01 | 0.1202 |
| Repeat size (continuous) | 348 | 0.011 | 0.00 | 0.2624 |
| FXPOI (y/n) | 255 | 0.416 | 0.00 | 0.3841 |
| AAM (age of onset) | 198 | −0.051 | 0.01 | 0.0933 |
AAM age at menopause, BMI body mass index, FXPOI fragile X–associated primary ovarian insufficiency.
aBonferroni-adjusted statistical significance p < 0.002 are bolded; Marginally significant models where significance was between 0.001 and 0.05 are underlined.