Fig. 4.

Post-mortemevaluation of mGluR1 at 16 months of age. Representative a [³H]ITDM autoradiograms and b mGluR1 immunohistochemistry for WT and HET mice. c [³H]ITDM specific binding as well as d mGluR1 immunoreactivity were higher in HET mice compared to WT littermates. WT: n = 17–19; HET: n = 17–18. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Scale bar = 2 mm. WT = wild-type, HET = heterozygous, CB = cerebellum, THAL = thalamus, STR = striatum, MC = motor cortex, HC = hippocampus