Table 4.

Demography and biochemical characteristics of acute coronary syndrome and control subjects compared in quartiles of serum Nrg4 levels.

Variables	Serum Nrg4 level					P value
	Study group	Q1 (≤0.09 ng/mL) ACS (n = 36) Control (n = 15)	Q2 (0.0901–0.31 ng/mL) ACS (n = 37) Control (n = 15)	Q3 (0.3101–1.37 ng/mL) ACS (n = 35) Control (n = 14)	Q4 (˃0.137 ng/mL) ACS (n = 36) Control (n = 13)
Age (years)	ACS	58.2 ± 12.1	64.3 ± 12.4	61 ± 11.4	59.6 ± 12.9	0.4
	Control	47 ± 9	46.7 ± 6.4	44.1 ± 9.6	43 ± 11.3	0.8
Gender (%) Male Female	ACS	57.9 42.1	50 50	45.5 54.5	50 50	0.8
	Control	40.7 59.3	25 75	23.1 76.9	33.3 66.7	0.7
BMI1 (Kg/m2)	ACS	24.4 ± 3.9	24.3 ± 5.6	25.2 ± 4.9	23.8 ± 3.3	0.9
	Control	26.8 ± 6.4	22.9 ± 3.6	27.2 ± 2.8	24.6 ± 4.2	0.2
Waist (cm)	ACS	89.3 ± 14.7	88.5 ± 9.3	92.8 ± 21.9	93 ± 9.3	0.7
	Control	81.2 ± 12.5	80.7 ± 7.9	90.5 ± 16.8	80 ± 11.1	0.2
LDL cholesterol (mg/dL)	ACS	90.1 ± 42.7	100.7 ± 35.9	111 ± 49.3	103.6 ± 32.8	0.5
	Control	126 ± 66.9	155.7 ± 56.4	122.5 ± 46.2	116.5 ± 14.8	0.5
HDL cholesterol (mg/dL)	ACS	45.4 ± 12.5	42.3 ± 10.5	38.4 ± 7	38.7 ± 10.2	0.2
	Control	*#60.9 ± 25.6	41 ± 2.3	#40.2 ± 9.9	*42.2 ± 7.8	0.02
Total cholesterol (mg/dL)	ACS	155.3 ± 51.9	166.5 ± 51.7	156.8 ± 57.3	172 ± 43.5	0.8
	Control	202.8 ± 54.7	216.5 ± 64.7	184.9 ± 48.8	175.2 ± 19.8	0.3
Triglyceride (mg/dL)	ACS	112.3 ± 54.6	141 ± 92.7	160.7 ± 77.9	192.1 ± 79.6	0.1
	Control	90.8 ± 23	88.7 ± 33.2	100.1 ± 38.8	75.6 ± 32.6	0.4
FBS (mg.dL)	ACS	114.5 ± 36.9	141.5 ± 75.2	123.4 ± 27.6	138 ± 78.7	0.4
	Control	85.2 ± 6.9	96.5 ± 8.3	96.8 ± 18	98.3 ± 20.2	0.5
Current Smoker (%)	ACS	37	27.8	9.1	12.5	0.1
	Control	2.3	1.5	15.4	8.3	0.6
Nrg4 (ng/mL)	ACS	*£0.06 ± 0.02	£0.18 ± 0.06	*£0.77 ± 0.26	2.7 ± 2.1	<0.0001
	Control	≠£0.04 ± 0.02	≠£0.23 ± 0.09	£0.85 ± 0.21	2.3 ± 0.7	<0.0001
hs-CRP (μg/mL)	ACS	167.7 ± 158.2	338.8 ± 120.5	295.1 ± 166.9	326.6 ± 208.1	0.3
	Control	205.7 ± 137	91.5 ± 79.5	146 ± 127.1	161.6 ± 182.6	0.8

^*P = 0.04.

^£P < 0.0001 versus Q4.

^≠P < 0.05 versus Q3.