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Effect of intraperitoneal pregnenolone 16α-carbonitrile (a rat PXR agonist) 40 mg/kg versus vehicle control (DMSO) for 6 days on the ABCA1 protein expression in the rat heart (left ventricle). The experiments were performed with five rats per experimental condition (n = 5). Data are presented as the mean + SD. ***P < 0.001 versus vehicle control; unpaired two-tailed Student’s t-test.
