Table 1.

Effect of rifampicin treatment on serum 4β-hydroxycholesterol, 25-hydroxycholesterol, 27-hydroxycholesterol and cholesterol values (n = 12). Data are presented as mean ± SD. The oxysterol to cholesterol ratios are presented as molar ratios × 10 000. ***P < 0.0001; paired two-tailed Student’s t-test.

	Rifampicin	Placebo
4βHC (ng/ml)	72.0 ± 21	35.0 ± 12***
4βHC/Cholesterol	0.42 ± 0.09	0.22 ± 0.07***
25HC (ng/ml)	2.83 ± 1.1	2.89 ± 1.2
25HC/Cholesterol	0.016 ± 0.005	0.018 ± 0.006
27HC (ng/ml)	42.3 ± 8.8	42.3 ± 8.3
27HC/Cholesterol	0.26 ± 0.08	0.27 ± 0.10
Cholesterol (mmol/l)	4.22 ± 0.8	4.03 ± 0.7
LDL (mmol/l)	2.38 ± 0.7	2.21 ± 0.5
HDL (mmol/l)	1.44 ± 0.2	1.36 ± 0.2
Triglycerides (mmol/l)	0.69 ± 0.3	0.77 ± 0.3