TABLE 4.
Genes differentially regulated after heat stress in C. lari RM2100 only.
| Category | Up-regulated | Down-regulated |
| Energy production and conversion | fdxB, ndh | mez, napH, oorB, petA, rdxA, torC |
| Cell cycle control, cell division, chromosome partitioning | – | ftsX |
| Amino acid transport and metabolism | pepE, selA, Cla_0593, Cla_0897, Cla_0458 | aroE, aspC, bioA, hisIE, livH, modC, pglE, sdaA, sdaC, selD |
| Nucleotide transport and metabolism | prsA | purE, pyrE, Cla_0004 |
| Carbohydrate transport and metabolism | rpe, Cla_1277 | tal, Cla_1361 |
| Coenzyme transport and metabolism | mobA, ribD, thiD, thiM, Cla_0686 | dxs, folP, hemC |
| Lipid transport and metabolism | aas, cdsA, dxr, fabZ | fabD, fabH3, ispE, pgpA, pgsA, Cla_1314 |
| Translation, ribosomal structure, and biogenesis | prfB, truB, Cla_0258 | gltX, leuS, rbfA, rplE, rplF, rplJ, rplX, tlyA, truA, Cla_0017, Cla_1325 |
| Transcription | Cla_0872, Cla_1081, Cla_1538 | npdA, rpoN, Cla_0784 |
| Replication, recombination, and repair | xth, Cla_0824 | dnaX, ligA, ligA-2, mutS, nth, rep, ruvA, uvrC, Cla_0401, Cla_0671, Cla_0836, Cla_0945 |
| Cell wall/membrane/envelope biogenesis | pseB, ptmB, Cla_0217 | kdsB, murC, mreC, pbpA, pglF, Cla_0642 |
| Cell motility | – | flgG, fliN |
| Posttranslational modification, protein turnover, chaperones | dnaJ, Cla_0589 + 90, Cla_1212 | hypA, Cla_1116 |
| Inorganic ion transport and metabolism | modB, cft | cmeF, Cla_0159, Cla_0643, Cla_0109 |
| Secondary metabolites biosynthesis, transport, and catabolism | Cla_0039, Cla_0565 | iamA, iamb, Cla_0207 |
| Signal transduction mechanism | Cla_1102, Cla_1204 | Cla_0781 |
| Intracellular trafficking, secretion, and vesicular transport | – | ctsG, exbD1, exbB1, secF, secY, Cla_0954 |
| Defense mechanisms | kpsM | Cla_1528 |
Summary of genes with up- or down-regulated expression level after heat stress and assignment to a functional category for C. lari RM2100. The log2 fold changes of expression level for each gene are shown in Supplementary Table S3.