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. 2020 Mar 27;11:364. doi: 10.3389/fphar.2020.00364

Table 8.

The cumulative excretion percentage of naringin and naringenin in human excreta (n=8 per groups, mean ± SD).

Dose (mg) In urine (% of dose) In feces (% of dose) In urine and feces
(% of dose)
Naringin Naringenin Total Naringin Naringenin Total
40 0.067 ± 0.039 6.69 ± 6.20 6.77 ± 6.20 0.122 ± 0.202 0.259 ± 0.734 0.305 ± 0.857 7.08 ± 7.06
80 0.037 ± 0.013 8.82 ± 5.46 8.87 ± 5.46 0.023 ± 0.036 0.034 ± 0.080 0.048 ± 0.109 8.92 ± 5.57
160 0.027 ± 0.014 9.67 ± 6.07 9.70 ± 6.08 0.016 ± 0.023 0.053 ± 0.150 0.092 ± 0.196 9.79 ± 6.28
160 (high-fat diet) 0.025 ± 0.008 9.50 ± 5.00 9.53 ± 5.00 9.85 ± 20.0 1.23 ± 2.54 10.7 ± 22.3 20.2 ± 27.3
320 0.033 ± 0.026 15.7 ± 8.73 15.7 ± 8.73 0.126 ± 0.325 0.592 ± 1.41 0.717 ± 1.74 16.4 ± 10.5
480 0.012 ± 0.004 10.4 ± 8.43 10.4 ± 8.43 0.023 ± 0.033 0.799 ± 1.92 0.821 ± 1.95 11.2 ± 10.4
160, three times a day 0.034 ± 0.014 28.3 ± 43.2 28.4 ± 43.2 0.563 ± 1.00 1.83 ± 2.32 2.36 ± 3.07 30.7 ± 46.2