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. 2020 Mar 27;11:371. doi: 10.3389/fphar.2020.00371

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Copyright © 2020 Piirsalu, Taalberg, Lilleväli, Tian, Zilmer and Vasar

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LPS treatment-induced changes in concentrations of (A) SCACs (C3), (B) hydroxylated LCACs (C16:1-OH), (C) citrulline, (D) KYN, (E) lysophosphatidylcholines (C20:3), (F) phosphatidylcholine diacyls (C36:1) and (G) sphingolipids (C16:0) in 129Sv mice 1.5 and 24 h after administration. Data was analyzed by two-way ANOVA followed by the Bonferroni post hoc test. *significant p value between saline and LPS treatment; ⁺significant p value between 1.5 h and 24 h LPS treatments. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001, ++++p ≤ 0.0001.