Table 3.
Effect of LPS treatment after 24 h on metabolite levels among Bl6 mice.
| Metabolites | Bl6 24 h LPS | |||
|---|---|---|---|---|
| Beta (β) | β (95% Cl) | t-value | p-value | |
| Δ body weight | −0.90 | −1.12, −0.68 | −8.64 | < 0.0001 |
| Citrulline (Cit) | −0.83 | −1.11, −0.54 | −6.05 | < 0.0001 |
| Acetylornithine (Ac-Orn) | −0.86 | −1.12, −0.60 | −6.90 | < 0.0001 |
| Kynurenine | 0.87 | 0.62, 1.12 | 7.23 | < 0.0001 |
| Putrescine | 0.88 | 0.64, 1.12 | 7.80 | < 0.0001 |
| lysoPC a C16:1 | −0.88 | −1.12, −0.64 | −7.64 | < 0.0001 |
| lysoPC a C20:3 | −0.88 | −1.12, −0.64 | −7.61 | < 0.0001 |
| lysoPC a C20:4 | −0.81 | −1.11, −0.52 | −5.78 | < 0.0001 |
| PC aa C36:1 | 0.85 | 0.57, 1.12 | 6.56 | < 0.0001 |
| PC aa C40:6 | 0.85 | 0.58, 1.12 | 6.68 | < 0.0001 |
| PC ae C38:2 | −0.85 | −1.12, −0.59 | −6.74 | < 0.0001 |
| SM (OH) C22:1 | 0.92 | 0.72, 1.12 | 9.58 | < 0.0001 |
| SM (OH) C22:2 | 0.89 | 0.66, 1.12 | 8.05 | < 0.0001 |
| SM C16:0 | 0.94 | 0.76, 1.12 | 11.02 | < 0.0001 |
| SM C24:0 | 0.85 | 0.57, 1.12 | 6.53 | < 0.0001 |
| SM C24:1 | 0.95 | 0.80, 1.11 | 12.84 | < 0.0001 |
| Hexoses (H1) | −0.78 | −1.10, −0.45 | −5.06 | < 0.0001 |
Statistically significant regression coefficients (β), confidence intervals (CI) and t- and p values (derived from GLM analysis) of log10-transformed metabolite levels.