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. 2020 Apr 3;25(4):040901. doi: 10.1117/1.JBO.25.4.040901

Table 1.

Summary of published values of OCT attenuation coefficient of human dermis in vivo. All results were calculated using single-scattering model.

Cutaneous tissue Reference Wavelength (nm) AFR (μm) Correction Location Sample number Attenuation (mm1)
CPSF SRF
Normal skin Schmitt et al.1 1300 200 to 400 Y N/A Forearm 2 subjects 4.6/4.7 (mean)
250 to 500 Finger 3.7/5.0 (mean)
100 to 500 Lip 2.0 (mean)
Kholodnykh et al.51 1300 100 Y N/A Forearm NS 10 to 13
Gong et al.35 1325 200 Y Y Forearm, thigh and lower leg 6 patients 6.3±0.5
Es’haghian et al.69 1300 250 Y Y Upper arm, abdomen, back, thigh and calf 7 patients 5.1±0.7
Welzel et al.74 1300 NS NS NS Including forearm 28 patients 3.6 to 4.2 (mean)
Psoriasis Welzel et al.74 1300 NS NS NS Including forearm 28 patients (17 after treatment) 2.9±0.9 (untreated)
3.8±1.7 (treated)
Burn scar Gong et al.35 1300 200 Y Y Forearm, thigh and lower leg 6 patients 3.8±0.4 (hypertrophic)
4.2±0.9 (normotrophic)

Note: Papers highlighted in bold present parametric attenuation coefficient imaging; others represent point measurements. AFR, axial fitting range; CPSF, confocal point spread function; N/A, not applicable; NS, not specified; SRF, sensitivity roll-off function.