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. 2020 Mar 15;59(6):783–787. doi: 10.2169/internalmedicine.3737-19

Figure 2.

Figure 2.

Domain of the PCSK9 gene. PCSK9 encodes a 692-amino-acid protein composed of a signal peptide, a pro-domain, catalytic, and C-terminal domains. Black arrows indicate the mutations reported thus far. Red arrows indicate a mutation identified in this study.