Table 2. Unadjusted and Adjusted Odds Ratio of Adverse Pathological Findings at Radical Prostatectomy for Each Clinical Characteristic.

Characteristic	Men, No.	Events, No.^a	Univariable analysis		Multivariable analysis
Characteristic	Men, No.	Events, No.^a	Unadjusted OR (95% CI)	P value	Adjusted OR (95% CI)	P value
Age	3191	377	1.01 (1.00-1.03)^b	.09	1.02 (1.00-1.04)^b	.07
>65 y	1075	133	1.08 (0.87-1.36)	.49	1.28 (1.00-1.62)	.048
≤65 y	2116	244	1 [Reference]	NA	1 [Reference]	NA
PSA level	3191	377	1.02 (1.01-1.036)^b	.004	0.99 (0.97-1.01)^b	.95
T category
≥2a	382	84	2.42 (1.85-3.17)	<.001	1.26 (0.93-1.71)	.13
1c	2809	293	1 [Reference]	NA	1 [Reference]	NA
Year of diagnosis	3191	377	0.87 (0.85-0.89)^b	<.001	0.89 (0.87-0.91)^b	<.001
Positive biopsy results, %	3191	377	1.03 (1.02-1.039)^b	<.001	1.02 (1.01-1.02)^b	<.001
PSA density	3191	377	3.23 (1.95-5.35)^b	<.001	4.28 (1.66-11.01)^b	.003

Abbreviations: NA, not applicable; OR, odds ratio; PSA, prostate-specific antigen; T, tumor.

^{^a}

Includes adverse pathological findings at prostatectomy, including T3/T4, R1, and/or Gleason score 8, 9, or 10.

^{^b}

Per 1-unit increase.