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. 2020 Apr 2;3(4):e202012. doi: 10.1001/jamanetworkopen.2020.2012

Table 2. Relative Risks and PAFs for Receiving Prescription Opioids by BMI Category in 565 930 Patients Aged 35 to 64 Years, athenahealth Network 2015 to 2017a.

BMI categoryb Relative risk (95% CI)c,d PAF, % (95% CI)c
Underweight 1.15 (1.10-1.21) 0.2 (0.2-0.3)
Normal weight 1 [Reference]
Overweight 1.08 (1.06-1.10) 2.1 (1.6-2.6)
Obese
I 1.24 (1.22-1.26) 5.0 (4.6-5.4)
II 1.33 (1.30-1.36) 3.9 (3.6-4.2)
III 1.48 (1.45-1.51) 3.9 (3.7-4.2)
IV 1.71 (1.65-1.77) 1.3 (1.2-1.5)
Total (overweight to obese IV) NA 16.2 (15.0-17.4)

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); NA, not applicable; PAF, population-attributable fraction.

a

eTable 1 in the Supplement provides the complete regression results. Sample interpretation: 5.0% of patients receiving prescription opioids could be avoided in the hypothetical situation in which those with a BMI of obese I had a normal BMI.

b

Underweight: BMI, 18.5 to 19.9; normal weight: 20.0 to 24.9; overweight: 25.0 to 29.9; obese I: 30.0 to 34.9; obese II: 35.0 to 39.9; obese III: 40.0 to 49.9; and obese IV: 50.0 to 80.0.

c

Adjusted for age, sex, race/ethnicity, region, urbanicity, and health insurance.

d

Relative risk calculated using a negative binomial model with robust SEs.