Squares represent mean ORs; error bars, 95% CIs. High bleeding risk is defined as patients 75 years of age or older, body weight (BW) lower than 60 kg, or a history of stroke or transient ischemic attack; low bleeding risk is defined as younger than 75 years of age, BW 60 kg or more, and no history of stroke or transient ischemic attack. AF indicates atrial fibrillation; CKD, chronic kidney disease; CPA, cardiac pulmonary arrest; CS, cardiogenic shock; IABP, intra-aortic balloon pump; NSTE-ACS, non-ST–segment elevation–acute coronary syndrome; STEMI, ST-segment elevation myocardial infarction; and VA-ECMO, venoarterial extracorporeal membrane oxygenation.