Table 4.
Baseline characteristics of patients by exacerbation category.
| Characteristics | Unreported exacerbations | Reported exacerbations | Odds ratio (95% CI) | P value | |
| Gender (male), n (%) | 123 (75.4) | 82 (83) | 1.61 (0.61-4.29) | .33 | |
| Age (years) | |||||
|
|
Mean (SD) | 65.5 (8.7) | 67.6 (8.3) | 1.04 (0.58-4.68) | .08 |
|
|
≥65, n (%) | 102 (62.5) | 68 (69) | 1.60 (0.67-3.81) | .28 |
| Active smokers, n (%) | 27 (16.6) | 12 (12) | 1.68 (0.53-5.26) | .37 | |
| BMI (kg/m2), mean (SD) | 26.6 (5.0) | 26.8 (4.6) | 1.02 (0.94-1.11) | .55 | |
| Number of comorbidities; mean (SD) ≥3, n (%) | 68 (41.7) | 55 (56) | 2.11 (0.94-4.73) | .07 | |
| Depression, n (%) | 8 (4.9) | 3 (3) | 0.55 (0.07-3.97) | .56 | |
| Anxiety, n (%) | 25 (15.3) | 26 (26) | 2.77 (0.99-7.70) | .05 | |
| Dyspnea (mMRCa) ≥2, n (%) | 129 (79.1) | 87 (88) | 2.73 (0.88-8.41) | .08 | |
| CATb questionnaire score ≥10, n (%) | 115 (70.5) | 80 (81) | 2.28 (0.88-5.94) | .09 | |
| Post-BD FEV1 %c predicted <50%, n (%) | 114 (69.9) | 74 (75) | 1.58 (0.64-3.91) | .32 | |
| Number of moderate-severe exacerbations in the last year ≥2, n (%) | 149 (91.4) | 96 (97) | 4.06 (0.69-23.72) | .12 | |
amMRC: modified Medical Research Council.
bCAT: Chronic Obstructive Pulmonary Disease Assessment Test.
cPost-BD FEV1 %: postbronchodilator FEV1 percent predicted.