Figure 1.

Histograms of z Values for Several Roadmap Tissues and Cell Types

Histograms of $z_i$’s and fitted mixture density f (green solid curve) and null subdensity $p_0{f}_0$ (blue dashed cuve) for Roadmap tissues/cell types E002, E030, E082, and E083. Violet colored histogram bars indicate estimated non-null counts. Yellow triangles on the positive horizontal axis mark the threshold values for local fdr(z)$\le 0.3$. Maximum likelihood estimates of mean and standard deviation of the empirical null distribution, and proportion $p_0$ of null cases are listed below each histogram.