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. 2020 Apr 2;106(4):513–524. doi: 10.1016/j.ajhg.2020.03.003

Figure 6.

Figure 6

Gene Set Analyses

For each gene set, the −log10(p values) from a Wilcoxon rank sum test of difference between brain local fdr for the mutations residing within 2 Mb of TSS of genes in the set, in ASD probands versus unaffected siblings are shown. The test is performed on the 100–10,000 mutations with the lowest brain local fdr in ASD probands and unaffected siblings, respectively, as described in Appendix A.