FIGURE 2.

Number of M pulmonis isolated from fetal tissues at gestational day 18

Dams were inoculated IV at GD 14 with (n = 5), 10¹ (n = 4), 10³ (n = 6), 10⁵ (n = 6), or 10⁷ (n = 5) CFU M pulmonis diluted in sterile Frey’s broth. Six fetal units were cultured per dam. Results are expressed as mean log CFU + standard error (SE) of M pulmonis isolated from each site. A, Placenta and amniotic fluid. There was an increase in number of CFU isolated from AF (P = .0001), and placenta (P = .0001), at 10⁷ compared to all other doses. B, Brain, lung, and spleen/liver. Similar results were found for brain (P = .0001), lung (P = .0001), and spleen/liver (P = .0001).

Riggs. Hematogenous infection of Sprague-Dawley rats with Mycoplasma pulmonis. Am J Obstet Gynecol 2008.