FIGURE 4.

Correlation between colonization of placenta or amniotic fluid and fetal tissues

CFU determinations for 126 matched samples were compared by regression analysis; overlapping points occurred if CFU were identical for samples. Correlations with placental CFU are shown on left and correlations with amniotic fluid CFU are shown on right. CFU of M pulmonis recovered from fetal lung (top) was correlated with recovery from the placenta (R = .923, R² = .85, P < .0001) and amniotic fluid (R = 0.863, R² = .743, P < .0001). M pulmonis was recovered from 2 fetal lungs in the absence of concomitant colonization of the paired placenta and from 8 fetal lungs in the absence of concomitant colonization of the paired amniotic fluid. CFU of M pulmonis recovered from fetal brain (middle) was correlated with recovery from the placenta (R = .923, R² = .85, P < .0001) and amniotic fluid (R = .863, R² = .743, P < .0001). M pulmonis was not recovered from any fetal brain in the absence of concomitant colonization of the paired placenta but was recovered from four fetal brains in the absence of concomitant colonization of the paired amniotic fluid. CFU of M pulmonis recovered from fetal spleen/liver (bottom) was correlated with recovery from the placenta (R = .95, R² = .901, P < .0001) and amniotic fluid (R = .884, R² = .78, P < .0001). M pulmonis was recovered from 2 fetal spleen/livers in the absence of concomitant colonization of the paired placenta and from 7 fetal spleen/livers in the absence of concomitant colonization of the paired amniotic fluid.

Riggs. Hematogenous infection of Sprague-Dawley rats with Mycoplasma pulmonis. Am J Obstet Gynecol 2008.