Table 1.

Proteins differentially isolated with the ends of the TGEV genome.

RNA bait	Accesion no.	Protein namea	Functionb	Mr	Masses matched/searched	Score/threshold/databasec	Speciesd	Ne
3′TGEV	gi|4504445	hnRNP A1	RNA transport, processing, and splicing	34289	11/32	107/70/m	H, R, P	3
3′TGEV	gi|4504447	hnRNP A2B1	RNA transport and splicing	36041	16/32	165/65/Hs	H, R, P	3⁎
3′TGEV	gi|5803036	hnRNP A0	RNA splicing	30993	5/18	76/65/Hs	H, R	3
3′TGEV	gi|3202000	hnRNP U	RNA processing and splicing	91164	19/35	136/78/nr	H, R, P	3⁎
3′TGEV	gi|44888326	hnRNP Q (SYNCRIP)	RNA processing and splicing	69818	27/66	321/76/nr	H, R, P	3⁎
3′TGEV	gi|693937	Polyadenylate binding protein (PABP)	RNA splicing and stabilization	70671	9/13	84/69/m	H	3⁎
3′TGEV	gi|5803036	Glutamyl-prolyl tRNA synthetase (EPRS)	Translation	172080	25/28	269/78/nr	H, R, P	3⁎
3′TGEV	gi|30583627	Arginyl-tRNA synthetase	Translation	76129	17/84	111/76/nr	H, P	2⁎
3′TGEV	gi|60415925	staphylococcal nuclease domain containing 1; p100 co-activator	Transcription and RNA interference	102709	29/40	363/76/nr	H, R	3
5′TGEV	gi|131529	Polypyrimidine tract-binding protein 1 (PTB)	RNA splicing	56671	1/1	82/50/nr	H	2

^aWhen alternative names are given, the one used in this study is shown in boldface.

^bBiological process according to Gene Ontology.

^cMascot scores are given in boldface. Mascot threshold scores indicate the limit score from which the identification was significant (p < 0.05). Searches were performed against the NCBI database without restrictions (nr). In the indicated cases taxonomy was restricted to humans (Hs) or mammals (m).

^dDifferent species in which the protein was identified in parallel experiments, coming from human Huh-7 (H), rodent BHK-pAPN (R) or porcine ST (P) cell extracts.

^eNumber of times that the protein was identified showing a clear binding preference for the indicated RNA bait. Asterisks indicate that the identification was confirmed by MS/MS.