Table 3.

Clinical outcomes of RFWB group versus component therapy (controls)

	RFWB (n = 31)	Control (n = 33)	P value
Primary outcome measures
Chest tube loss 0–4 h CCCU, mL/kg (range)	7.1 (0.6–30.0)	5.7 (1.8–45.6)	.76
Chest tube loss 4–24 h CCCU, mL/kg (range)	7.7 (2.0–34.6)	11.8 (4.0–44.1)	.03
Bleeding assessed as moderate or severe	17 (55%)	27 (82%)	.03
Secondary outcome measures
Inotropic support score (ISS) at 4 h CCCU	6.6 (0–20.0)	9.5 (0–20.0)	.53
Inotropic support score (ISS) at 24 h CCCU	3.3 (0–9.9)	6.6 (0–14.9)	.002
Ventilation in hours, median (range)	119 (28–480)	164 (54–912)	.04
CCCU LOS in days, median (range)	5 (3–20)	7 (1–39)	.17
Hospital LOS in days, median (range)	12 (6–36)	18 (7–79)	.02
Transfusion characteristics
Blood produce exposure, mean units ± SD	3.2 ± 1.9	6.9 ± 3.8	<.0001
Transfusion requirements postop, mL/kg (range)	33 (0–177)	43 (4–160)	.55
Age of donor blood products, days	1.9 ± 0.3	13.6 ± 7.7	<.0001

RFWB, Reconstituted fresh whole blood; CCCU, cardiac critical care unit; LOS, length of stay; SD, standard deviation.