Table 2.
Examples of specific viruses that may be transmitted in transplanted cells and cause serious diseases and currently available screening tests
| Viruses | Diagnostic tests |
|---|---|
| Viruses of human origin | |
| HIV-1/2 | NAT, serologya |
| HBV | NAT, serologya |
| HCV | NAT, serologya |
| HTLV-I/II | NAT, serologya |
| CMV | NAT, culture, EM, serologya |
| EBV | NAT, serologya |
| Prions | WB, ELISA |
| Viruses of animal origin | |
| BVDV | NAT (RT-PCR), EM |
| Hantaan virus | APT, EM |
| Reovirus-3 | APT, EM |
| Sendai virus | APT, EM |
| Lactic dehydrogenase virus | APT, EM |
| Lymphocitic choriomeningitis virus | APT, EM |
| Prions | WB, ELISA |
| Unknown viruses | EM |
NAT: nucleic acid test (PCR, RT-PCR); EM: electron microscopy; APT: antibodies production tests (MAP, RAP, HAP); WB: Western blot; ELISA: enzyme-linked immunosorbent assay; BVDV: bovine viral diarrhea virus.
a
Serology: for donors of biological products.