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. 2020 Apr 3;11:144. doi: 10.1186/s13287-020-01650-6

Table 2.

Upregulated genes in SKPs induced by epidermal stem cells

Gene Description Log2(FC) Fold change
Fgf5 Fibroblast growth factor 5 8.53 370.00
Osm Oncostatin M 8.53 370.00
Fgf16 Fibroblast growth factor 16 8.28 310.00
Il6 Interleukin 6 6.34 81.27
Pdgfb Platelet derived growth factor, B polypeptide 3.87 14.67
Csf3 Colony stimulating factor 3 (granulocyte) 3.49 11.22
Lama1 Laminin, alpha 1 2.82 7.08
Lamc2 Laminin, gamma 2 2.79 6.89
Lamb3 Laminin, beta 3 2.50 5.65
Lama5 Laminin, alpha 5 2.38 5.21
Lamc3 Laminin gamma 3 2.28 4.86
Angpt2 Angiopoietin 2 1.89 3.72
Lama3 Laminin, alpha 3 1.70 3.24
Pgf Placental growth factor 1.60 3.04
Pdgfa Platelet-derived growth factor, alpha 1.53 2.89
Tnc Tenascin C 1.49 2.81
Efna1 Ephrin A1 1.18 2.27
Col6a3 Collagen, type VI, alpha 3 1.07 2.09
Fgf13 Fibroblast growth factor 13 1.05 2.07

RNA-Seq revealed upregulated (> 2-fold) genes in the category of secreted proteins in SKPs after being cultured in mixture with epidermal stem cells for 24 h