Table 18.
Rhinosinusitis consensus research definitions and clinical trial guidelines
| Type of rhinosinusitis |
||||
|---|---|---|---|---|
| Acute (presumed bacterial) rhinosinusitis | CRS without nasal polyposis | CRS with nasal polyposis | AFRS | |
| Criteria for diagnosis | ||||
| Pattern of symptoms |
|
Symptoms present for ≥12 wk | ||
| Symptoms for diagnosis | Requires:
|
Requires ≥2 of the following symptoms:
|
Requires ≥2 of the following symptoms:
|
Requires ≥1 of the following symptoms:
|
| Objective documentation | Requires either
|
Requires both
|
Requires both
|
Requires
|
Other possible, but not required, documentation measures:
|
||||
Patients who have intracranial extension, have orbital cellulitis, or require hospitalization are considered to have severe disease but should be excluded from clinical trials of uncomplicated acute (presumed bacterial) rhinosinusitis.