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. 2020 Apr 2;21:303. doi: 10.1186/s13063-020-4224-4

Table 2.

Sample size per treatment arm for various values of ICC and (radj)

radj
0.4 0.3 0.2 0.1 NOa
ICC
0.06 102 120 138 150 150
0.07 126 150 180 198 204
0.08 156 204 258 300b 312
0.09 210 318 468 630 714

ICC intra-cluster correlation coefficient, radj correlation coefficient between outcome and adjustment covariates

aNo adjustment for baseline covariates

bRequired no. of patients per arm