Table 2.

Routine screening for thrombocytopenia

Item	Diagnosis
Blood test; C-reactive protein (CRP); procalcitonin (PCT)	Severe infection; hematological disease
Prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen (Fib), D-dimer (DD), fibrindegradation products (FDP)	DIC; the cause should be determined
Alanine aminotransferase (ALT), aspartate aminotransferase(AST), creatinine (Cr), total bilirubin (TBil)	Thrombocytopenia due to liver and renal impairment
Lactic acid dehydrogenase (LDH)	Hemolytic anemia; paroxysmal nocturnal hemoglobinuria
Vitamin B12, folic acid	Malnutrition-associated thrombocytopenia
EBvirus, cytomegalovirus (CMV), hepatitis B virus (HBV), hepatitis C virus (HCV), HIV	Viral infection
Antinuclear antibodies (ANA), rheumatoid factor (RF)	Autoimmune diseases such as SLE, Sjogren’s syndrome, and RA